Could you make a 'new', 'better' computer from the C64 just by reprogramming the PLA?

Hi all.

It seems to me that what makes the C64 "the C64" is the way the PLA is programmed so it maps the different chips as I/O addresses in the memory space.

But as seen in the many different computers based on the 6502, the way the 65xx architecture is designed is that "every thing is a memory address", similar to *nix philosophy of "everything is a file".

So, leaving compatibility out, could you make a 'better' computer out of a standard C64, just by reprogramming the PLA and moving the memory addresses used by the different chips in a better more efficient way?

Thanks all.

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Saludos y cerveza.